Tell your doctor if you experience any of them. These symptoms can be associated with other cancers and many non-cancerous conditions. pain or sense of fullness below the ribs.shortness of breath during normal activity.swollen lymph nodes in the neck, underarm, stomach, or groin.It may be discovered during a routine blood test or checkup, or when a blood test is done for another health problem. ![]() People with CLL/SLL often have no signs or symptoms in the early stages of the disease. Keep in mind, however, that having one or more risk factors for CLL does not mean you will develop the disease. being of North American or European descent.having relatives with CLL/SLL or cancer of the lymph system.When the primary manifestation of the condition is enlarged lymphoid tissues, the condition is usually then referred to as small lymphocytic lymphoma (SLL).Ĭertain factors may increase a person's chance of developing CLL/SLL. In time, it can spread to other parts of the body that normally contain lymphocytes, such as the lymph nodes (in the neck, abdomen, and groin, under the arms, and around the collarbone), as well as the liver and the spleen. CLL most often develops from B lymphocytes.ĬLL begins in the bone marrow but then, as the abnormal lymphocytes multiply, they typically are released into the blood stream. This can result in infection, anemia, and easy bleeding. As they pile up in the blood and bone marrow, they crowd out healthy white blood cells, red blood cells, and platelets. Even in high numbers, they cannot fight infection as well as normal cells. When the condition results primarily in a high number of circulating lymphocytes, it is referred to as CLL. These cells do not function properly and they do not undergo normal removal from the blood stream. In CLL/SLL, too many blood stem cells turn into abnormal lymphocytes. Natural killer cells, which also can kill cancer cells and viruses.T lymphocytes, which can destroy virus-infected cells, foreign cells, and cancer cells.B lymphocytes, which make antibodies to help protect the body from germs.Lymphoid stem cells develop into three types of infection-fighting lymphocytes: The myeloid cells become mature blood cells: white blood cells, red blood cells, and platelets. Normally, a person's immature blood stem cells develop into myeloid and lymphoid stem cells. Most people with CLL are middle-aged or older. CLL/SLL usually grows slowly compared to other leukemias and lymphomas, and it may not cause symptoms for some time.ĬLL is one of four main types of leukemia. What is Chronic Lymphocytic Leukemia (CLL)?Ĭhronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) is a cancer that occurs when the bone marrow and/or lymph nodes make too many lymphocytes, a type of white blood cell.
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